LY-3200882
CAS No. | 1898283-02-7 | Cat. No. | BCP20882 |
Name | LY-3200882 | ||
Synonyms | LY 3200882; LY3200882; | ||
Formula | C24H29N5O3 | M. Wt | 435.52 |
Description | LY-3200882 is an orally active TGFbeta inhibitor. LY3200882 targets transforming growth factor-beta (TGFb), with potential antineoplastic activity. Upon administration, LY3200882 specifically targets and binds to TGFb, which prevents both the binding of TGFb to its receptor TGFbR and TGFb-mediated signal transduction. This may lead to a reduction in TGFb-dependent proliferation of cancer cells. | ||
Pathways | TGF beta/Smad Wnt/Stem Cell | ||
Targets | BMP/TGF beta Receptor TGF β/Smad |
Structure
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