LY-3200882

  • Chemical Properties
CAS No. 1898283-02-7 Cat. No. BCP20882
Name LY-3200882
Synonyms LY 3200882; LY3200882;
Formula C24H29N5O3 M. Wt 435.52
  • Biological Activity
Description LY-3200882 is an orally active TGFbeta inhibitor. LY3200882 targets transforming growth factor-beta (TGFb), with potential antineoplastic activity. Upon administration, LY3200882 specifically targets and binds to TGFb, which prevents both the binding of TGFb to its receptor TGFbR and TGFb-mediated signal transduction. This may lead to a reduction in TGFb-dependent proliferation of cancer cells.
Pathways TGF beta/Smad  Wnt/Stem Cell 
Targets BMP/TGF beta Receptor TGF β/Smad 

Structure

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