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SB-747651A dihydrochloride Chemical Structure

SB-747651A dihydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP46273CAS No. :1781882-72-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1781882-72-1 Cat. No. BCP46273
Related Products 607372-46-3(SB-747651A)
Name SB-747651A dihydrochloride
Synonyms SB-747651A 2HCl ;SB 747651A dihydrochloride; SB-747651A dihydrochloride;
SMILES CCN C2=C(C=NC=C2CNC3CCNCC3)N=C1C4=N
Chemical Name
Formula C16H24Cl2N8O M. Wt 415.32
Purity 98% Storage Store at 4-8°C
Description SB-747651A dihydrochloride is a potent, ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor (IC50 = 11 nM in an in vitro kinase assay); targets the N-terminal kinase domain. Inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells. Blocks IL-10 production in macrophages.
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