ITX-5061 HCl New
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CAS No. | 1252679-52-9 | Cat. No. | BCP30784 |
Name | ITX-5061 HCl | ||
Synonyms | ITX-5061 hydrochloride ; ITX 5061 HCl ; ITX506 HCl;ITX5061 hydrochloride;ITX 5061 hydrochloride; | ||
SMILES | CC(C)(C)C1=CC(=C(C(=C1)NS(=O)(=O)C)OC)NC(=O)C(=O)C2=CC=C(C3=CC=CC=C32)OCCN4CCOCC4.Cl | ||
Chemical Name | |||
Formula | C30H38ClN3O7S | M. Wt | 620.16 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ITX-5061 is a Hepatitis C Virus Entry Inhibitor or a scavenger receptor B1 antagonist. ITX 5061 has entered phase 1 clinical trials in hepatitis C virus (HCV)-infected humans. ITX-5061 possesses a unique mechanism of action that prevents the hepatitis C virus from entering liver cells and has demonstrated potent preclinical antiviral activity against all HCV genotypes. Preclinical studies have shown ITX-5061 to be a potent and selective inhibitor of HCV entry into hepatocytes, capable of preventing virus binding/fusion and cell to cell spread, suggesting ITX-5061 may reduce re-infection rates following liver transplant. |
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