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CAS No. | 1703793-34-3 | Cat. No. | BCP20175 |
Name | Avapritinib | ||
Synonyms | BLU-285; BLU 285; BLU285; | ||
SMILES | CC(C1=CC=C(C=C1)F)(C2=CN=C(N=C2)N3CCN(CC3)C4=NC=NN5C4=CC(=C5)C6=CN(N=C6)C)N | ||
Chemical Name | |||
Formula | C26H27FN10 | M. Wt | 498.57 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BLU-285, also known as Avapritinib, is a potent and selective inhibitor of PDGFRα D842V and KIT Exon 17 mutants and is being developed as a highly targeted therapy for SM, a disorder of the mast cells in which a KIT Exon 17 mutation is the primary driver of disease. BLU-285 is currently being developed by Blueprint. |
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