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Avapritinib Chemical Structure

Avapritinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP20175CAS No. :1703793-34-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1703793-34-3 Cat. No. BCP20175
Name Avapritinib
Synonyms BLU-285; BLU 285; BLU285;
SMILES CC(C1=CC=C(C=C1)F)(C2=CN=C(N=C2)N3CCN(CC3)C4=NC=NN5C4=CC(=C5)C6=CN(N=C6)C)N
Chemical Name
Formula C26H27FN10 M. Wt 498.57
Purity 98% Storage Store at 4-8°C
Description BLU-285, also known as Avapritinib, is a potent and selective inhibitor of PDGFRα D842V and KIT Exon 17 mutants and is being developed as a highly targeted therapy for SM, a disorder of the mast cells in which a KIT Exon 17 mutation is the primary driver of disease. BLU-285 is currently being developed by Blueprint.
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