Avapritinib
CAS No. | 1703793-34-3 | Cat. No. | BCP20175 |
Name | Avapritinib | ||
Synonyms | BLU-285; BLU 285; BLU285; | ||
Formula | C26H27FN10 | M. Wt | 498.57 |
Description | BLU-285, also known as Avapritinib, is a potent and selective inhibitor of PDGFRα D842V and KIT Exon 17 mutants and is being developed as a highly targeted therapy for SM, a disorder of the mast cells in which a KIT Exon 17 mutation is the primary driver of disease. BLU-285 is currently being developed by Blueprint. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | c Kit |
Structure
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