AZ Dyrk1B 33 New
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CAS No. | 1679330-37-0 | Cat. No. | BCP41848 |
Name | AZ Dyrk1B 33 | ||
Synonyms | AZ-Dyrk1B-33; | ||
SMILES | CC1=NC=CC(=N1)C2=CN(C3=C2C=CN=C3)CC4=CC=CC=C4 | ||
Chemical Name | |||
Formula | C19H16N4 | M. Wt | 300.36 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AZ Dyrk1B 33 is a potent and selective ATP-competitive Dyrk1B kinase inhibitor with IC50 value of 7 nM. It shows better selectivity than AZ 191 and shows no off-target effects against a panel of 124 kinases tested. It displays distinct cellular effects when compared to DYRK1B knockdown through siRNA and has been demonstrated cellular in vitro activity. |
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