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AZ Dyrk1B 33 Chemical Structure

AZ Dyrk1B 33

Data Sheet For research use only. Not for human use.
Cat. No. :BCP41848CAS No. :1679330-37-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1679330-37-0 Cat. No. BCP41848
Name AZ Dyrk1B 33
Synonyms AZ-Dyrk1B-33;
SMILES CC1=NC=CC(=N1)C2=CN(C3=C2C=CN=C3)CC4=CC=CC=C4
Chemical Name
Formula C19H16N4 M. Wt 300.36
Purity 98% Storage Store at 4-8°C
Description AZ Dyrk1B 33 is a potent and selective ATP-competitive Dyrk1B kinase inhibitor with IC50 value of 7 nM. It shows better selectivity than AZ 191 and shows no off-target effects against a panel of 124 kinases tested. It displays distinct cellular effects when compared to DYRK1B knockdown through siRNA and has been demonstrated cellular in vitro activity.
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