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CAS No. | 147591-46-6 | Cat. No. | BCP27795 |
Name | ID-8 | ||
Synonyms | ID 8; ID8; | ||
SMILES | CC1=C(C2=C(N1C3=CC=C(C=C3)OC)C=C(C=C2)O)[N+](=O)[O-] | ||
Chemical Name | |||
Formula | C16H14N2O4 | M. Wt | 298.29 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ID-8 is a DYRK inhibitor. ID-8 could support Wnt-induced human embryonic stem cell proliferation and survival without differentiation. Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) is the target of the small molecule ID-8. Its role in human pluripotent cell renewal was confirmed by DYRK knockdown in human embryonic stem cells. |
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