Umbralisib sulfate New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP24681CAS No. ：1532533-75-7Purity：98%

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Chemical Properties&Biological Activity

CAS No.	1532533-75-7	Cat. No.	BCP24681
Name	Umbralisib sulfate
Synonyms	TGR-1202 sulfate; RP-5264 sulfate;
SMILES	CC(C)OC1=C(C=C(C=C1)C2=NN(C3=NC=NC(=C23)N)C(C)C4=C(C(=O)C5=C(O4)C=CC(=C5)F)C6=CC(=CC=C6)F)F.OS(=O)(=O)O
Chemical Name
Formula	C31H26F3N5O7S	M. Wt	669.63
Purity	98%	Storage	Store at 4-8°C
Description	Umbralisib sulfate is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib sulfate exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib sulfate can be used for haematological malignancies reseach.

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