Umbralisib sulfate
| CAS No. | 1532533-75-7 | Cat. No. | BCP24681 |
| Name | Umbralisib sulfate | ||
| Synonyms | TGR-1202 sulfate; RP-5264 sulfate; | ||
| Formula | C31H26F3N5O7S | M. Wt | 669.63 |
| Description | Umbralisib sulfate is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib sulfate exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib sulfate can be used for haematological malignancies reseach. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
Structure
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