Anakinra New
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CAS No. | 143090-92-0 | Cat. No. | BCP30242 |
Name | Anakinra | ||
Synonyms | Kineret;Unii-9013duq28k;Interleukin1 receptor antagonist (huMan isoforM x reduced),N2-L-Methionyl- (9CI); | ||
SMILES | CC C)(C)C(=O)OC | ||
Chemical Name | |||
Formula | C20H23N5O7S2 | M. Wt | 509.56 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Anakinra is a recombinant human nonglycosylated interleukin-1 (IL-1) receptor antagonist with potential antineoplastic activity. Anakinra binds to the IL-1 receptor, thereby blocking the binding of the IL-1 to and activation of its receptor. Blockade of IL-1 activity may inhibit the cascade of downstream pro-angiogenic factors such as vascular endothelial cell growth factor, tumor necrosis factor-alpha, and IL-6, resulting in inhibition of tumor angiogenesis. |
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