Anakinra

  • Chemical Properties
CAS No. 143090-92-0 Cat. No. BCP30242
Name Anakinra
Synonyms Kineret;Unii-9013duq28k;Interleukin1 receptor antagonist (huMan isoforM x reduced),N2-L-Methionyl- (9CI);
Formula C20H23N5O7S2 M. Wt 509.56
  • Biological Activity
Description Anakinra is a recombinant human nonglycosylated interleukin-1 (IL-1) receptor antagonist with potential antineoplastic activity. Anakinra binds to the IL-1 receptor, thereby blocking the binding of the IL-1 to and activation of its receptor. Blockade of IL-1 activity may inhibit the cascade of downstream pro-angiogenic factors such as vascular endothelial cell growth factor, tumor necrosis factor-alpha, and IL-6, resulting in inhibition of tumor angiogenesis.
Pathways Others Pathway 
Targets Interleukin Related 

Structure

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