ITX-5061 HCl

CAS No.	1252679-52-9	Cat. No.	BCP30784
Name	ITX-5061 HCl
Synonyms	ITX-5061 hydrochloride ; ITX 5061 HCl ; ITX506 HCl；ITX5061 hydrochloride；ITX 5061 hydrochloride;
Formula	C30H38ClN3O7S	M. Wt	620.16

Description	ITX-5061 is a Hepatitis C Virus Entry Inhibitor or a scavenger receptor B1 antagonist. ITX 5061 has entered phase 1 clinical trials in hepatitis C virus (HCV)-infected humans. ITX-5061 possesses a unique mechanism of action that prevents the hepatitis C virus from entering liver cells and has demonstrated potent preclinical antiviral activity against all HCV genotypes. Preclinical studies have shown ITX-5061 to be a potent and selective inhibitor of HCV entry into hepatocytes, capable of preventing virus binding/fusion and cell to cell spread, suggesting ITX-5061 may reduce re-infection rates following liver transplant.
Pathways	Microbiology/Virology MAPK Pathway
Targets	p38 MAPK HCV

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