Efonidipine hydrochloride ethanolate New
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CAS No. | 111011-76-8 | Cat. No. | BCP33396 |
Name | Efonidipine hydrochloride ethanolate | ||
Synonyms | Efonidipine hydrochloride monoethanolate;Efonidipine HCl H2O;NZ-105 hydrochloride monoethanolate; | ||
SMILES | CCO.CC1=C(C(C(=C(N1)C)P2(=O)OCC(CO2)(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5.Cl | ||
Chemical Name | |||
Formula | C36H45ClN3O8P | M. Wt | 714.18 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Efonidipine hydrochloride monoethanolate is a selective blocker of L-type and T-type Ca2+ channels. Displays minimal inhibition of N- and P/Q-type channels and no inhibition of R-type channels. R(-) and S(+)-enantiomers display different channel selectivity; S(+)-Efonidipine blocks L-type and T-type channels whereas R(-)-Efonidipine displays selectivity for T-type channels. Exhibits antihypertensive activity. |
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