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Efonidipine hydrochloride ethanolate Chemical Structure

Efonidipine hydrochloride ethanolate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP33396CAS No. :111011-76-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 111011-76-8 Cat. No. BCP33396
Name Efonidipine hydrochloride ethanolate
Synonyms Efonidipine hydrochloride monoethanolate;Efonidipine HCl H2O;NZ-105 hydrochloride monoethanolate;
SMILES CCO.CC1=C(C(C(=C(N1)C)P2(=O)OCC(CO2)(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5.Cl
Chemical Name
Formula C36H45ClN3O8P M. Wt 714.18
Purity 98% Storage Store at 4-8°C
Description Efonidipine hydrochloride monoethanolate is a selective blocker of L-type and T-type Ca2+ channels. Displays minimal inhibition of N- and P/Q-type channels and no inhibition of R-type channels. R(-) and S(+)-enantiomers display different channel selectivity; S(+)-Efonidipine blocks L-type and T-type channels whereas R(-)-Efonidipine displays selectivity for T-type channels. Exhibits antihypertensive activity.
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