Efonidipine hydrochloride ethanolate

  • Chemical Properties
CAS No. 111011-76-8 Cat. No. BCP33396
Name Efonidipine hydrochloride ethanolate
Synonyms Efonidipine hydrochloride monoethanolate;Efonidipine HCl H2O;NZ-105 hydrochloride monoethanolate;
Formula C36H45ClN3O8P M. Wt 714.18
  • Biological Activity
Description Efonidipine hydrochloride monoethanolate is a selective blocker of L-type and T-type Ca2+ channels. Displays minimal inhibition of N- and P/Q-type channels and no inhibition of R-type channels. R(-) and S(+)-enantiomers display different channel selectivity; S(+)-Efonidipine blocks L-type and T-type channels whereas R(-)-Efonidipine displays selectivity for T-type channels. Exhibits antihypertensive activity.
Pathways Ion Channel/Membrane Transporter 
Targets Calcium Channel 

Structure

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