Glaucocalyxin A New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 79498-31-0 | Cat. No. | BCP30380 |
| Name | Glaucocalyxin A | ||
| Synonyms | LeukaMenin F; Wangzaozin B; Leucamenin F; | ||
| SMILES | CC1(C2CC(C34C(C2(CCC1=O)C)CCC(C3O)C(=C)C4=O)O)C | ||
| Chemical Name | |||
| Formula | C20H28O4 | M. Wt | 332.43 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Glaucocalyxin A, which is extracted from the herbs of Rabdosia rubescens, inhibited Akt phosphorylation, suppressed proliferation, and promoted apoptosis in a dose-dependent manner, but not in normal glial cells. Glaucocalyxin A activated caspase-3, decreased BAD phosphorylation, and reduced the expression of X-linked inhibitor of apoptosis protein. Glaucocalyxin A inhibited collagen-stimulated tyrosine phosphorylation of Syk, LAT, and phospholipase Cγ2, the signaling events in collagen receptor GPⅥ pathway. | ||
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