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CAS No. | 2169905-68-2 | Cat. No. | BCP49263 |
Name | Vemtoberant | ||
Synonyms | APD418; APD 418; APD-418; | ||
SMILES | CCN1C=C(C(=O)C2=CC=CC=C21)S(=O)(=O)N3CCC4(CC3)CC(CO4)NCC(COC5=CC(=CC=C5)S(=O)(=O)C)O | ||
Chemical Name | |||
Formula | C29H37N3O8S2 | M. Wt | 619.75 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Vemtoberant is a β3-adrenergic receptor (AdrR) antagonist for treatment of decompensated heart failure. Unlike current inotrope therapies, Vemtoberant improves cardiac contractility with minimal negative impact on heart rate, blood pressure, and myocardial oxygen consumption. Vemtoberant has undergone Phase 2 trials for those in heart failure with reduced ejection fraction. |
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