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CAS No. | 1562338-42-4 | Cat. No. | BCP19909 |
Related Products | 1562338-39-9(Branaplam hydrochloride) | ||
Name | Branaplam | ||
Synonyms | LMI-070;LMI070;LMI 070;NVS-SM1; | ||
SMILES | OC1=CC(C2=CNN=C2)=CC=C1C3=NN=C(OC4CC(C)(C)NC(C)(C)C4)C=C3.[H]Cl | ||
Chemical Name | |||
Formula | C22H27N5O2 | M. Wt | 393.48 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Branaplam, also known as NVS-SM1 and LMI-070, is a highly potent, selective and orally active small molecule SMN2 splicing modulator as a potential treatment for SMA Type 1 (Spinal Muscular Atrophy) .NVS-SM1 works by increasing the amount of functional SMN protein produced by the “back-up” gene, SMN2, through modifying its splicing. |
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