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CAS No. | 1333146-24-9 | Cat. No. | BCP23690 |
Name | ILK-IN-1 | ||
Synonyms | ILK-IN-2;OSU-T315 analog;OSU-T315 (1,5-regioisomer);ILK inhibitor 22(1,5); | ||
SMILES | CNC(=O)CCC1=NN(C(=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(F)(F)F)C4=CC=C(C=C4)N5CCNCC5 | ||
Chemical Name | |||
Formula | C30H30F3N5O | M. Wt | 533.59 |
Purity | 98% | Storage | Store at 4-8°C |
Description | OSU-T315 (1,5-regioisomer) is a potent and specific integrin-linked kinase (ILK) inhibitor which inhibits PDK2 function in the AKT pathway activation, showing a specific mechanism of abrogating the AKT pathway and inhibition of BCR activity in the leukemic cell. OSU-T315 also acts as a selective inhibitor of biofilm formation. |
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