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CAS No. | 1206163-45-2 | Cat. No. | BCP23893 |
Name | Solcitinib | ||
Synonyms | GSK2586184; GSK 2586184; GSK-2586184; GSK2586184A; GSK-2586184A; GSK 2586184A; GLPG-0778; GLPG 0778; GLPG0778; G154578; | ||
SMILES | CC1(CN(C1)C(=O)C2=CC=C(C=C2)C3=CC=CC4=NC(=NN43)NC(=O)C5CC5)C | ||
Chemical Name | |||
Formula | C22H23N5O2 | M. Wt | 389.45 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively; Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis. |
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