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CAS号 | 209984-57-6 | 货号 | BCP02531 |
中文名 | LY411575 | ||
英文名 | LY411575 | ||
中文别名 | |||
英文别名 | LY 411575;LY-411575; LSN-411575; LSN 411575; LSN411575; | ||
SMILES | O=C1[C@@H](NC([C@@H](NC([C@](C2=CC(F)=CC(F)=C2)O)=O)C)=O)C3=CC=CC=C3C(C=CC=C4)=C4N1C | ||
化学名称 | |||
分子式 | C26H23F2N3O4 | 分子量 | 479.48 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | LY 411575, also known as LSN-411575, is potent, cell permeable and selective γ-secretase inhibitor that reduces Aβ/42 after acute or chronic treatment, and blocks Notch activation. The gamma secretase inhibitor, activating pPKC alpha intracellular pathway could be suggested to prevent or reduce downstream toxic events, representing a useful strategy to counteract Alzheimer's disease. |
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