所有产品分类
所有产品
信号通路
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
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- Smoothened/Smo
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- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
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- FAAH
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- nAChR
- COX
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- mAChR
- NFκB
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-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
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- Xanthine Oxidase
- Pyruvate Kinase
- Mitochondrial Metabolism
- ALDH
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- Serine Protease
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- E1 E2 E3 Enzyme
- Elastase
- PAI1
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- Phosphatase
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- Integrase
- Phosphodiesterase/PDE
- Phospholipase
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
研究领域
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
天然产物
抗体
多肽
催化剂
杂质对照品
医药中间体
基础原料
VEGFR
结构式 | 货号 | 产品名称 | CAS号 |
---|
BCP02336 | 苏尼替尼 | 557795-19-4 | |
Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.
|
BCP49401 | OPT-302 新 | OPT-302 | |
OPT-302 is a novel inhibitor of vascular endothelial growth factor (VEGF)-C and VEGF-D.
|
BCP48941 | Tyrphostin AG1433 新 | 168835-90-3 | |
Tyrphostin AG1433 is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).
|
BCP25508 | SU1498 新 | 168835-82-3 | |
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM).
|
BCP46895 | WAY-340935 新 | 737818-56-3 | |
WAY-340935 (VEGFR2-IN-2) is a potent and selective VEGFR2 inhibitor with an IC50 of 19.32 nM. VEGFR2-IN-2 can be used for researching
|
BCP46664 | CEP-11981 新 | 856691-93-5 | |
CEP-11981 is an orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR) and Tie2 receptor tyrosine kinases with potential antiangiogenic and antineoplastic activities. Pan-VEGFR/Tie2 tyrosine kinase inhibitor CEP-11981 selectively binds to VEGFR and Tie2 receptor tyrosine kinases, which may result the inhibition of endothelial cell migration, proliferation and survival and the inhibition of tumor cell proliferation and tumor cell death.
|
BCP46143 | 宁格替尼 新 | 1394820-69-9 | |
Ningetinib is a novel tyrosine kinase inhibitor, targeted at c-Met, Axl, VEGFR-2, Mer and Flt3.
|
BCP45190 | 替沃扎尼盐酸盐一水合物 新 | 682745-41-1 | |
Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.
|
BCP40284 | XL-092 新 | 2367004-54-2 | |
XL092 is an investigational, next-generation oral TKI that targets VEGF receptors, MET, AXL, MER and other kinases implicated in the growth and spread of cancer.
|
BCP37847 | HS-1793 新 | 927885-00-5 | |
HS-1793, inhibits hypoxia-induced HIF-1α and VEGF expression, and migration in human prostate cancer cells.
|