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研究领域
- Metabolic Disease
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天然产物
抗体
多肽
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杂质对照品
医药中间体
基础原料
BMI1
| 结构式 | 货号 | 产品名称 | CAS号 |
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BCP20909 | PTC-028 | 1782970-28-8 |
A novel potent, selective, orally bioavailable BMI-1 inhibitor with potent anti-MM activity against primary MM cells (IC50=10-100 nM); decreases BMI-1 levels by posttranslational modification, selectively inhibits cancer cells in clonal growth and viability assays (IC50=100 nM), without effeccts on normal cells; exhibits significant antitumor activity in mouse model of ovarian cancer.
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BCP09028 | PTC-209 | 315704-66-6 |
PTC-209 is a potent and selective BMI-1 inhibitor, and results in irreversible reduction of cancer–initiating cells (CICs).
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