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YO-01027 结构式

YO-01027

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货号 :BCP02556CAS号 :209984-56-5纯度:98%
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  • 基本信息与产品描述
CAS号 209984-56-5 货号 BCP02556
中文名 YO-01027
英文名 YO-01027
中文别名
英文别名 Dibenzazepine;DBZ;LY 411575;LY411575;LY-411575;
SMILES
化学名称
分子式 C26H23F2N3O3 分子量 479.48
纯度 98% 配送 惯例下常温包邮
产品描述 Increasing concentrations of YO-01027 administered to APPL- or Notch-expressing cells leads to the progressive accumulation of APPL CTF fragments and a decrease in NICD production in a strictly dose-dependent manner. [1] 10 μM of YO-01027 reduces breast cancer stem cells (BCSC) number and activity. [2] A recent research indicates YO-01027 impairs mucin protein MUC16 biosynthesis in a concentration-dependent manner in undifferentiated cells at both preconfluent and confluent stages through Notch inhibition, but not in postmitotic stratified cells.
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