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Chloride Channel

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Chloride Channel

结构式 货号 产品名称 CAS号
Endovion 结构式
 BCP42713 Endovion 265646-85-3
Endovion is an ANO1 inhibitor.
NPPB 结构式
 BCP36797 NPPB 107254-86-4
NPPB is a blocker of the outwardly rectifying chloride channel (ORCC).
R(+)-IAA-94 结构式
 BCP32714 R(+)-IAA-94 54197-31-8
R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels.
Monna 结构式
 BCP32415 Monna 1572936-83-4
MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 = 80 nM).
CLP-290 结构式
 BCP25040 CLP-290 1181083-81-7
CLP-290 is a novel KCC2 modulator and prodrug of CLP-257, highly selective for KCC2 over related Cl- transporters.
Chlorotoxin 结构式
 BCP30217 氯代毒素 163515-35-3
Chlorotoxin is a 36 amino-acid peptide from the venom of the Israeli scorpion Leiurus quinquestriatus with anticancer activity.
Adjudin 结构式
 BCP13328 Adjudin 252025-52-8
Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect. Adjudin is also a potent Cl- channel blocker.
DCPIB 结构式
 BCP30868 DCPIB 82749-70-0
DCPIB is a potent and selective volume-sensitive anion channel (VSAC) blocker, swell in various cardiovascular tissues (IC50 = 4.1 μM in CPAE cells). It inhibits glucose-stimulated insulin in intact β-cells, and reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro.
CaCCinh-A01 结构式
 BCP26187 CaCCinh-A01 407587-33-1
CaCCinh-A01 is an inhibitor of both TMEM16A and calcium-activated chloride channel (CaCC) with IC50s of 2.1 and 10 μM, respectively.
Lubiprostone 结构式
 BCP08672 卢比前列腺素 333963-40-9
Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion.
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