![cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid 结构式](https://img.biochemsafebuy.com/uploads/img/952578-68-6_BCP02273.png "cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid 结构式")
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| CAS号 | 952578-68-6 | 货号 | BCP02273 |
| 中文名 | MK-0752 | ||
| 英文名 | cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid | ||
| 中文别名 | |||
| 英文别名 | MK0752;MK 0752; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C21H21ClF2O4S | 分子量 | 442.9 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | MK-0752 is identified as a moderately potent γ-secretase inhibitor, which reduces Aβ40 in a dose-dependent manner with an IC50 of 5 nM in human SH-SY5Y cells.In vitro, MK-0752 blocks Notch-intracellular domain (ICD) cleavage and its subsequent nuclear translocation. | ||
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