LY411575
CAS号 | 209984-57-6 | 货号 | BCP02531 |
中文名 | LY411575 | ||
英文名 | LY411575 | ||
中文别名 | |||
英文别名 | LY 411575;LY-411575; LSN-411575; LSN 411575; LSN411575; | ||
分子式 | C26H23F2N3O4 | 分子量 | 479.48 |
生物活性 | LY 411575, also known as LSN-411575, is potent, cell permeable and selective γ-secretase inhibitor that reduces Aβ/42 after acute or chronic treatment, and blocks Notch activation. The gamma secretase inhibitor, activating pPKC alpha intracellular pathway could be suggested to prevent or reduce downstream toxic events, representing a useful strategy to counteract Alzheimer's disease. | ||
信号通路 | Protease/Metabolic Enzyme Neuro Signaling Pathway Wnt/Stem Cell | ||
靶 点 | Gamma secretase Notch |
结构式
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