所有产品分类
所有产品
信号通路
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天然产物
抗体
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医药中间体
基础原料
CGRP Receptor
结构式 | 货号 | 产品名称 | CAS号 |
---|
BCP24753 | 乌布吉泮 新 | 1374248-77-7 | |
Ubrogepant (MK-1602) is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine.
|
BCP46799 | Vazegepant hydrochloride 新 | 1414976-20-7 | |
Vazegepant hydrochloride is a highly affinity CGRP receptor antagonist (hCGRP Ki= 0.023 nM). Vazegepant is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.
|
BCP46647 | Vazegepant 新 | 1337918-83-8 | |
Vazegepant, also known as Zavegepant, BHV-3500 and BMS 742413, is a highly potent, selective and structurally unique small molecule CGRP receptor antagonist. Vazegepant is the first and only CGRP receptor antagonist for intranasal administration currently in development for the acute treatment of migraine.
|
BCP42168 | 硫酸利美戈潘 新 | 1374024-48-2 | |
Rimegepant is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines.
|
BCP29403 | BIBN 4096BS | 204697-65-4 | |
BIBN 4096BS is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP.
|
BCP28575 | 瑞美吉泮 新 | 1289023-67-1 | |
Rimegepant is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.
|
BCP29018 | MK-8031 | 1374248-81-3 | |
MK-8031, also known as Atogepant, is a calcitonin gene-related peptide receptor antagonist.
|
BCP27622 | MK 3207 盐酸盐 | 957116-20-0 | |
MK-3207 (Hydrochloride) is a potent and orally bioavailable CGRP receptor antagonist with IC50 of 0.12 nM and Ki of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3.
|
BCP07257 | Telcagepant | 781649-09-0 | |
MK-0974 is a highly potent, selective, and orally bioavailable CGRP receptor antagonist, which may be valuable in the acute treatment of migraine.
|
BCP02225 | MK 3207 | 957118-49-9 | |
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist. In common with other CGRP receptor antagonists, MK-3207 displays lower affinity for human CGRP receptors from other species, including canine and rodent.
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