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Avagacestat 结构式

塞来西布

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP01770CAS号 :1146699-66-2纯度:98%
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  • 基本信息与产品描述
CAS号 1146699-66-2 货号 BCP01770
中文名 塞来西布
英文名 Avagacestat
中文别名
英文别名 BMS-708163;BMS708163;BMS 708163;
SMILES O=C(N)[C@H](N(CC1=CC=C(C2=NOC=N2)C=C1F)S(=O)(C3=CC=C(Cl)C=C3)=O)CCC(F)(F)F
化学名称
分子式 C20H17ClF4N4O4S 分子量 520.89
纯度 98% 配送 惯例下常温包邮
产品描述 Avagacestat, also known as BMS-708163, is an oral GSI designed for selective inhibition of Aβ synthesis currently in development for the treatment of mild to moderate and predementia AD. In addition to the desired effect on Aβ synthesis, GSIs affect Notch processing, which is thought to mediate some toxic adverse effects reported with this drug class.
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