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RSK

结构式 货号 产品名称 CAS号
SL 0101-1 结构式
 BCP21457 SL 0101-1 77307-50-7
SL0101 is a highly specific RSK inhibitor. SL0101 showed improved in vitro biological stability while maintaining specificity for RSK. These results should facilitate the development of RSK inhibitors derived from SL0101 as anticancer agents.
AT7867 dihydrochloride 结构式
 BCP30936 AT7867 dihydrochloride 1431697-86-7
AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.
Carnosol 结构式
 BCP20030 鼠尾草苦内脂 5957-80-2
Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC50 of ~5.5 μM.
GSK-25 结构式
 BCP21619 GSK-25 874119-56-9
GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
S6K-18 结构式
 BCP21624 S6K-18 1265789-88-5
S6K-18 is a highly selective inhibitor of S6K1, with an IC(50) of 52nM.
Clindamycin palmitate hydrochloride 结构式
 BCP28438 克林霉素棕榈酸酯盐酸盐 25507-04-4
Clindamycin Palmitate HCl a ribosomal translocation and protein synthesis inhibitor that displays efficacy against MRSA. It is also occasionally used to treat Plasmodium.
M2698 结构式
 BCP19488 M2698 1379545-95-5
M2698, also known as MSC-2363318A, is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier.
Bupivacaine 结构式
 BCP21825 布比卡因 2180-92-9
Bupivacaine, is a medication used to freeze tissue in a specific area. It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space.
AD80 结构式
 BCP25106 AD80 1384071-99-1
AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity.
Bupivacaine hydrochloride 结构式
 BCP22697 盐酸布比卡因 14252-80-3
Bupivacaine Hydrochloride is a local anaesthetic drug belonging to the amino amide group.
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