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PI3K

结构式 货号 产品名称 CAS号
GSK2292767 结构式
 BCP24323 GSK2292767 1254036-66-2
GSK2292767 is a potent and selective PI3Kδ inhibitor.
Umbralisib sulfate 结构式
 BCP24681 Umbralisib sulfate 1532533-75-7
Umbralisib sulfate is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively.
Umbralisib R-enantiomer 结构式
 BCP24683 Umbralisib R-enantiomer 1532533-69-9
Umbralisib R-enantiomer is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202.
Umbralisib tosylate 结构式
 BCP24684 Umbralisib tosylate 1532533-72-4
Umbralisib tosylate is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib tosylate exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib tosylate can be used for haematological malignancies reseach.
TGR1202 racemate 结构式
 BCP24685 TGR1202 racemate 1532533-65-5
TGR-1202 R-enantiomer is is the less active enantiomer of TGR-1202 (Umbralisib), TGR-1202 is a potent, selective, orally available PI3Kδ inhibitor with IC50 of 22 nM..
SRX3177 结构式
 BCP48567 SRX3177 2241237-51-2
SRX3177 is a novel potent triple action inhibitor, targeting BRD, PI3K, and CDK.
PI3K/mTOR Inhibitor-2 结构式
 BCP48401 PI3K/mTOR Inhibitor-2 1848242-58-9
PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor.
AZD-3458 结构式
 BCP47242 AZD-3458 2132961-46-5
AZD3458 is a potent and remarkably selective PI3Kγ inhibitor for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ.
Disitertide 结构式
 BCP46789 地司特泰 272105-42-7
Disitertide is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide is also a PI3K inhibitor and an apoptosis inducer.
IHMT-PI3Kδ-372 结构式
 BCP46775 IHMT-PI3Kδ-372 2429889-62-1
IHMT-PI3Kδ-372 is a potent and selective phosphatidylinositol 3-kinase δ (PI3Kδ) inhibitor with an IC50 of 14 nM in the biochemical assay.
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