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| CAS号 | 1058137-84-0 | 货号 | BCP21230 |
| 中文名 | 德立替尼盐酸盐 | ||
| 英文名 | Lucitanib hydrochloride | ||
| 中文别名 | |||
| 英文别名 | E-3810 HCI;E3810; E-3810; E 3810; AL3810; AL 3810; AL-3810; | ||
| SMILES | CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC.Cl | ||
| 化学名称 | |||
| 分子式 | C26H25N3O4.HCl | 分子量 | 479.95 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Lucitanib is a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. VEGFR/FGFR dual kinase inhibitor E-3810 inhibits VEGFR-1, -2, -3 and FGFR-1, -2 kinases in the nM range, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Both VEGFRs and FGFRs belong to the family of receptor tyrosine kinases that may be upregulated in various tumor cell types. | ||
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