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CAS号 | 39025-23-5 | 货号 | BCP07472 |
中文名 | 孕二烯二酮 | ||
英文名 | (Z)-Guggulsterone | ||
中文别名 | 没药甾酮Z;木苦甾酮;顺式-固甾酮;孕二烯二酮Z;香胶甾酮; | ||
英文别名 | Z-Guggulsterone;Guggulsterone Z; | ||
SMILES | C/C=C/1\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C | ||
化学名称 | |||
分子式 | C21H28O2 | 分子量 | 312.45 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signaling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo. |
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