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TAS-115 mesylate 结构式

TAS-115 mesylate

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货号 :BCP34015CAS号 :1688673-09-7纯度:98%
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  • 基本信息与产品描述
CAS号 1688673-09-7 货号 BCP34015
中文名 TAS-115 mesylate
英文名 TAS-115 mesylate
中文别名
英文别名 TAS 115 methanesulfonate;TAS-115 methanesulfonate;TAS115 mesylate;
SMILES CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=C(C=C(C=C3)NC(=S)NC(=O)CC4=CC=CC=C4)F.CS(=O)(=O)O
化学名称
分子式 C28H27FN4O7S2 分子量 614.66
纯度 98% 配送 惯例下常温包邮
产品描述 TAS-115 is a c-MET and VEGFR inhibitor which is selective and specific in vitro. In vivo studies, TAS-115 suppressed the progression of MET-inactivated tumor completely through blocking angiogenesis without toxicity and it also induced marked tumor shrinkage and prolonged survival in animal model. In Dec 2013, Phase-I development was ongoing in Japan. In Dec 2014, Taiho Pharmaceutical completed a phase I trial for Solid tumours in Japan. In Apr 2016, preclinical data was presented.
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