德立替尼盐酸盐
| CAS号 | 1058137-84-0 | 货号 | BCP21230 |
| 中文名 | 德立替尼盐酸盐 | ||
| 英文名 | Lucitanib hydrochloride | ||
| 中文别名 | |||
| 英文别名 | E-3810 HCI;E3810; E-3810; E 3810; AL3810; AL 3810; AL-3810; | ||
| 分子式 | C26H25N3O4.HCl | 分子量 | 479.95 |
| 生物活性 | Lucitanib is a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. VEGFR/FGFR dual kinase inhibitor E-3810 inhibits VEGFR-1, -2, -3 and FGFR-1, -2 kinases in the nM range, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Both VEGFRs and FGFRs belong to the family of receptor tyrosine kinases that may be upregulated in various tumor cell types. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | VEGFR FGFR | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！