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CAS号 | 1256565-36-2 | 货号 | BCP32869 |
中文名 | PTC299 | ||
英文名 | PTC299 | ||
中文别名 | |||
英文别名 | PTC-299;PTC 299; | ||
SMILES | COC1=CC=C(C=C1)C2C3=C(CCN2C(=O)OC4=CC=C(C=C4)Cl)C5=C(N3)C=CC(=C5)Cl | ||
化学名称 | |||
分子式 | C25H20Cl2N2O3 | 分子量 | 467.34 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PTC299 is a potent, orally bioavailable VEGFA inhibitor, targets dihydroorotate dehydrogenase (DHODH), resulting in cell growth inhibition and differentiation in leukemias, including acute myeloid leukemia, linking DHODH regulation and stress-induced VEGFA and angiogenesis. |
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