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Tivozanib hydrochloride hydrate 结构式

替沃扎尼盐酸盐一水合物

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货号 :BCP45190CAS号 :682745-41-1纯度:98%
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  • 基本信息与产品描述
CAS号 682745-41-1 货号 BCP45190
关联产品 475108-18-0(替沃扎尼)
中文名 替沃扎尼盐酸盐一水合物
英文名 Tivozanib hydrochloride hydrate
中文别名 盐酸替沃扎尼一水合物;
英文别名 Tivozanib HCl H2O;
SMILES CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl.O.Cl
化学名称
分子式 C22H22Cl2N4O6 分子量 509.34
纯度 98% 配送 惯例下常温包邮
产品描述 Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities. Tivozanib binds to and inhibits VEGFRs 1, 2 and 3, which may result in the inhibition of endothelial cell migration and proliferation, inhibition of tumor angiogenesis and tumor cell death. VEGFR tyrosine kinases, frequently overexpressed by a variety of tumor cell types, play a key role in angiogenesis.
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