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Glumetinib 结构式

Glumetinib

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货号 :BCP31155CAS号 :1642581-63-2纯度:98%
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  • 基本信息与产品描述
CAS号 1642581-63-2 货号 BCP31155
中文名 Glumetinib
英文名 Glumetinib
中文别名
英文别名 SCC244; SC-C244; SCC 244;
SMILES CN1C=C(C=N1)C2=CN3C(=NC=C3S(=O)(=O)N4C5=C(C=N4)N=CC(=C5)C6=CN(N=C6)C)C=C2
化学名称
分子式 C21H17N9O2S 分子量 459.49
纯度 98% 配送 惯例下常温包邮
产品描述 Glumetinib is a novel, potent and highly selective inhibitor of c-Met in MET-dependent cancer models. SCC244 showed subnanomolar potency against c-Met kinase activity and high selectivity versus 312 other tested protein kinases, making it one of the most selective c-Met inhibitors described to date. Moreover, this inhibitor profoundly and specifically inhibits c-Met signal transduction and thereby suppresses the c-Met-dependent neoplastic phenotype of tumor and endothelial cells.
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