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Sitravatinib 结构式

司曲替尼

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货号 :BCP29099CAS号 :1123837-84-2纯度:98%
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  • 基本信息与产品描述
CAS号 1123837-84-2 货号 BCP29099
中文名 司曲替尼
英文名 Sitravatinib
中文别名
英文别名 MGCD516; MGCD-516; MGCD 516; MG516; MG 516; MG-516;
SMILES COCCNCC1=CN=C(C=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
化学名称
分子式 C33H29F2N5O4S 分子量 629.68
纯度 98% 配送 惯例下常温包邮
产品描述 Sitravatinib, also known as MGCD516 or MG516, is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth. MGCD516 treatment resulted in significant blockade of phosphorylation of potential driver RTKs and induced potent anti-proliferative effects in vitro. MGCD516 treatment of tumor xenografts in vivo resulted in significant suppression of tumor growth.
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