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CAS号 | 1002304-34-8 | 货号 | BCP01384 |
中文名 | AMG-208 | ||
英文名 | AMG-208 | ||
中文别名 | |||
英文别名 | AMG208;AMG 208; | ||
SMILES | |||
化学名称 | |||
分子式 | C22H17N5O2 | 分子量 | 383.41 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | AMG-208 shows the potent inhibition of kinase c-Met activity with IC50 of 9 nM in a cell-free assay. Besides, AMG-208 treatment also leads to the inhibition of HGF-mediated c-Met phosphorylation in PC3 cells with IC50 of 46 nM. [1] Incubation of AMG-208 with rat and human liver microsomes in the presence of NADPH qualitatively yields C6-phenylarene oxidation products as the major metabolites. [1] Pre-incubation of AMG-208 with human liver microsomes for 30 minutes shows a potent time-dependent in |
Tags:AMG-208 供应商,AMG-208 购买,AMG-208 生产,AMG-208 批量,AMG-208 供应,AMG-208 订购,AMG-208 采购