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CAS号 | 1384426-12-3 | 货号 | BCP29982 |
中文名 | NT-157 | ||
英文名 | NT-157 | ||
中文别名 | |||
英文别名 | NT 157; NT157;Tyrphostin NT157;Tyrphostin NT-157; | ||
SMILES | C1=C(C=C(C(=C1O)O)O)CNC(=CC=C2C=C(C(=O)C(=C2)Br)O)S | ||
化学名称 | |||
分子式 | C16H14BrNO5S | 分子量 | 412.26 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | NT157 is a selective inhibitor of IRS-1/2. NT157 significantly affected the cells' migratory ability. NT-157 induced cytostatic effects, as evidenced by G2/M cell cycle arrest, and did not affect apoptosis. NT157 has the potential to inhibit IGF-1R and STAT3 signaling pathways in cancer cells and stroma cells of TME leading to a decrease in cancer cell survival. |
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