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CAS号 | 781628-99-7 | 货号 | BCP42957 |
中文名 | SBI-477 | ||
英文名 | SBI-477 | ||
中文别名 | |||
英文别名 | SBI 477; SBI477; | ||
SMILES | COC1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC(=C(C=C3)OCC(=O)N4CCOCC4)OC | ||
化学名称 | |||
分子式 | C24H25N3O6S | 分子量 | 483.54 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA. SBI-477 inhibited triacylglyceride (TAG) synthesis and enhanced basal glucose uptake in human skeletal myocytes. SBI-477 stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4). |
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