NT-157
CAS号 | 1384426-12-3 | 货号 | BCP29982 |
中文名 | NT-157 | ||
英文名 | NT-157 | ||
中文别名 | |||
英文别名 | NT 157; NT157;Tyrphostin NT157;Tyrphostin NT-157; | ||
分子式 | C16H14BrNO5S | 分子量 | 412.26 |
生物活性 | NT157 is a selective inhibitor of IRS-1/2. NT157 significantly affected the cells' migratory ability. NT-157 induced cytostatic effects, as evidenced by G2/M cell cycle arrest, and did not affect apoptosis. NT157 has the potential to inhibit IGF-1R and STAT3 signaling pathways in cancer cells and stroma cells of TME leading to a decrease in cancer cell survival. | ||
信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
靶 点 | Insulin Receptor IGF1R |
结构式
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