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Vorolanib 结构式

Vorolanib

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货号 :BCP30430CAS号 :1013920-15-4纯度:98%
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  • 基本信息与产品描述
CAS号 1013920-15-4 货号 BCP30430
中文名 Vorolanib
英文名 Vorolanib
中文别名
英文别名 CM-082; X-82; CM082; X82; CM 082; X 82;
SMILES CC1=C(NC(=C1C(=O)NC2CCN(C2)C(=O)N(C)C)C)C=C3C4=C(C=CC(=C4)F)NC3=O
化学名称
分子式 C23H26FN5O3 分子量 439.48
纯度 98% 配送 惯例下常温包邮
产品描述 Vorolanib is an orally available small molecule dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs) with antiangiogenic and antineoplastic activities. Vorolanib inhibits all isoforms of VEGFR and PDGFR, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Both VEGFRs and PDGFRs are receptor tyrosine kinases that may be upregulated in various tumor cell types. Vorolanib has been shown to reduce tissue toxicity by 95 percent compared with first-generation kinase inhibitors.
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