Vorolanib 新
参考资料
仅供科学研究,不可用于个人用途。
规格 | 价格(CNY) | 是否现货 | 购买咨询 |
---|---|---|---|
2.00 mg | ¥1700.00 | In-stock | 购买咨询 |
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CAS号 | 1013920-15-4 | 货号 | BCP30430 |
中文名 | Vorolanib | ||
英文名 | Vorolanib | ||
中文别名 | |||
英文别名 | CM-082; X-82; CM082; X82; CM 082; X 82; | ||
SMILES | CC1=C(NC(=C1C(=O)NC2CCN(C2)C(=O)N(C)C)C)C=C3C4=C(C=CC(=C4)F)NC3=O | ||
化学名称 | |||
分子式 | C23H26FN5O3 | 分子量 | 439.48 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Vorolanib is an orally available small molecule dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs) with antiangiogenic and antineoplastic activities. Vorolanib inhibits all isoforms of VEGFR and PDGFR, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Both VEGFRs and PDGFRs are receptor tyrosine kinases that may be upregulated in various tumor cell types. Vorolanib has been shown to reduce tissue toxicity by 95 percent compared with first-generation kinase inhibitors. |
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