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Halofuginone 结构式

常山酮

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP07016CAS号 :55837-20-2纯度:98%
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  • 基本信息与产品描述
CAS号 55837-20-2 货号 BCP07016
中文名 常山酮
英文名 Halofuginone
中文别名
英文别名 Tempostatin;RU-19110;RU 19110;RU19110;
SMILES C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O
化学名称
分子式 C16H17BrClN3O3 分子量 414.69
纯度 98% 配送 惯例下常温包邮
产品描述 Halofuginone, also known as RU-19110, is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters.
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