常山酮
CAS号 | 55837-20-2 | 货号 | BCP07016 |
中文名 | 常山酮 | ||
英文名 | Halofuginone | ||
中文别名 | |||
英文别名 | Tempostatin;RU-19110;RU 19110;RU19110; | ||
分子式 | C16H17BrClN3O3 | 分子量 | 414.69 |
生物活性 | Halofuginone, also known as RU-19110, is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. | ||
信号通路 | TGF beta/Smad Wnt/Stem Cell | ||
靶 点 | TGF β/Smad |
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
- 全国免费电话:400-099-8200
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!