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CAS号 | 614749-78-9 | 货号 | BCP30149 |
中文名 | SM16 | ||
英文名 | SM16 | ||
中文别名 | |||
英文别名 | SM-16; SM 16; | ||
SMILES | O=C(C1(CC2)CCC2(C3=NC(C4=CC=C(OCO5)C5=C4)=C(C6=NC(C)=CC=C6)N3)CC1)N | ||
化学名称 | |||
分子式 | C25H26N4O3 | 分子量 | 430.51 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | SM16 was shown to bind with high affinity to ALK5 kinase ATP binding site using a competitive binding assay and biacore analysis. SM16 blocked TGF-beta and activin-induced Smad2/3 phosphorylation and TGF-beta-induced plasminogen activator inhibitor (PAI)-luciferase activity in cells. |
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