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Pirfenidone 结构式

吡非尼酮

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP04473CAS号 :53179-13-8纯度:98%
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  • 基本信息与产品描述
CAS号 53179-13-8 货号 BCP04473
中文名 吡非尼酮
英文名 Pirfenidone
中文别名 哌非尼酮;5-甲基-1-苯基-2-(1H)-吡啶酮;
英文别名 AMR69; AMR-69; AMR 69;
SMILES CC1=CN(C(=O)C=C1)C2=CC=CC=C2
化学名称
分子式 C12H11NO 分子量 185.22
纯度 98% 配送 惯例下常温包邮
产品描述 Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.
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