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CAS号 | 521984-48-5 | 货号 | BCP19304 |
中文名 | SIS3 HCl | ||
英文名 | SIS3 HCl | ||
中文别名 | |||
英文别名 | SIS-3;SIS 3; | ||
SMILES | |||
化学名称 | |||
分子式 | C28H28ClN3O3 | 分子量 | 489.99 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | SIS3 Reduces the TGF-β1-Dependent Increase in Phosphorylation and DNA Binding of Smad3. SIS3 has no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. SIS3 can block excessive ECM production from the TGF-β1-treated normal fibroblasts and scleroderma fibroblasts, the model of cells with autocrine TGF-β signaling in vitro. |
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