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Ertiprotafib 结构式

Ertiprotafib

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP44500CAS号 :251303-04-5纯度:98%
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  • 基本信息与产品描述
CAS号 251303-04-5 货号 BCP44500
中文名 Ertiprotafib
英文名 Ertiprotafib
中文别名
英文别名 PTP-112; PTP112; PTP 112;
SMILES CC1=CC(=CC(=C1OC(CC2=CC=CC=C2)C(=O)O)C)C3=C4C(=C(SC4=C(C5=CC=CC=C53)Br)C)C
化学名称
分子式 C31H27BrO3S 分子量 559.52
纯度 98% 配送 惯例下常温包邮
产品描述 Ertiprotafib is an inhibitor of the protein tyrosine phosphatase 1B (PTP1B) and dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist with hypoglycemic and anti-lipidemic activity. Ertiprotafib inhibits PTP1B preventing the dephosphorylation of the insulin receptor, which improves insulin sensitivity and decreases blood glucose levels. In addition, this agent is able to stimulate both PPAR alpha and gamma thereby further improving glucose homeostasis and reducing triglyceride (TG) and free fatty acid levels. Ertiprotafib was also shown to be a potent inhibitor of IkappaB kinase beta (IKKbeta), which cotributes to its anti-inflammatory properties.
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