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CAS号 | 186139-09-3 | 货号 | BCP44501 |
中文名 | Trodusquemine | ||
英文名 | Trodusquemine | ||
中文别名 | |||
英文别名 | MSI-1436; MSI1436; MSI 1436; MSI-1436C; MSI1436C; MSI 1436C; Aminosterol 1436; Aminosterol1436; Aminosterol-1436; | ||
SMILES | CC(C)C(CCC(C)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)NCCCNCCCCNCCCN)C)O)C)OS(=O)(=O)O | ||
化学名称 | |||
分子式 | C37H72N4O5S | 分子量 | 685.07 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Trodusquemine is a protein tyrosine phosphatase PTP-1B inhibitor potentially for the treatment of type 2 diabetes. Trodusquemine significantly enhanced insulin-stimulated tyrosine phosphorylation of insulin receptor (IR) beta and STAT3, direct targets of PTP1B, in HepG2 cells in vitro and/or hypothalamic tissue in vivo. |
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